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CSMLS Workforce Integration Project Report
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Hypercoagulation - Thrombophilia

 Hypercoagulation - Thrombophilia (9852-09) Update your knowledge about the control mechanisms with this complex system and learn what turns the process off and prevents clotting and plugging up blood vessels. Your study of thrombotic disease includes the cause and risks to the patient. You will consider the impact of oral contraception, hereditary risk factors, Antithrombin II deficiency, and protein C deficiency on the coaguation system.

Code 9852-09
Niveau Supérieur

Prix membres

$0

Prix non-membres

$135

 

Renseignements additionnels

PEP hours: 19
CPS/ART credits: 1.1

 

Learning Outcomes:
  • Define the term hypercoagulation and thrombophilia
  • Give an overview of normal hemostasis
  • Describe how built in controls prevent excessive thrombin production
  • Tabulate the common risk factors for both venous and arterial thrombosis
  • Review the effect of the dysfibrinogenemia in thrombosis
  • Outline the effects of oral contraception ( estrogen ) on the coagulation system
  • Tabulate the known hereditary risk factors for thrombophilia
  • Describe in detail the features of Antithrombin III deficiency
  • Describe in detail the features of protein C deficiency
  • Outline the relationship between protein C and protein S
  • Tabulate the relative levels of AT III, protein C and protein S seen in different physiological states
  • Draw a diagram of the biochemical pathways relevant to homocysteinemia
  • Describe the types of phospholipid antibodies and their relevance to thrombophilia
  • Describe the mutations seen in Factor V Leiden and Prothrombin 20210A
  • Review the progress in the search for other mutations that affect the APC-R test
  • Describe the structural and genetic features of Antithrombin III, Protein C and Protein S.
Instructor: John Chapman, FCSMLS, FIMLS, CLSp(H)
Prerequisites: None
Textbook: N/A
Equipment: Computer with Internet is required
Start Date: Upon registration
Completion: Up to 52 weeks
Version Date: November 2009